Article
Anti-CCP antibodies are associated with early age at onset in patients with rheumatoid arthritis.
Joint bone spine - 1 Mar 2011
Diaz Francisco J, Rojas-Villarraga Adriana, Salazar Juan C, Iglesias-Gamarra Antonio, Mantilla Ruben D, Anaya Juan-Manuel
Abstract excerpt
OBJECTIVES: To determine factors influencing the age at onset of rheumatoid arthritis (RA). METHODS: A sample of 152 Colombian patients was investigated. Hazard ratios (HRs) that measured the effect size of risk factors on the age at RA onset were computed by using Cox regression models. RESULTS: Positive anti-CCP antibodies were associated with an increased risk of early RA onset (HR = 1.60; 95% confidence...
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