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Article

Genetic characterization of HIV type 1 Nef-induced vesicle secretion.

AIDS research and human retroviruses - 1 Feb 2010

Ali Syed A, Huang Ming-Bo, Campbell Patrick E, Roth William W, Campbell Tamika, Khan Mahfuz, Newman Gale, Villinger Francois, Powell Michael D, Bond Vincent C

Abstract excerpt

The HIV-1 Nef protein is known to be secreted, and our group has shown that Nef is secreted from nef-transfected and HIV-1-infected cells in small exosome-like vesicles (d. 40-100 nm). The role of secreted Nef remains to be fully characterized. Thus, it is important to characterize the nature of and the mechanisms regulating Nef secretion. We hypothesized that specific structural domains on the Nef protein...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20156100
DOI: 10.1089/aid.2009.0068
PMCID: PMC2835390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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