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Article

Coatomer protein complex I is required for efficient secretion of dengue virus non-structural protein 1

2024-10-13

Abstract excerpt

<h4>ABSTRACT</h4> Secreted non-structural protein 1 (sNS1) is an important orthoflavivirus pathogenic factor that can induce vascular leakage; a key symptom of severe dengue disease. Given the role of sNS1 in dengue pathogenesis, defining the molecular mechanisms of NS1 secretion may contribute towards development of NS1-targeting antiviral therapies. To this end, we performed a customised membrane-trafficking si...

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Literature Corpus work
aafd82a9-7d9b-5e2e-a3a2-9a53b4812367
DOI
10.1101/2024.10.12.618008
Open publication

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Coatomer protein complex I is required for efficient secretion of dengue virus non-structural protein 1DOI 10.1101/2024.10.12.618008
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