Article
HIV Type 1 Nef Is Released from Infected Cells in CD45 <sup>+</sup> Microvesicles and Is Present in the Plasma of HIV-Infected Individuals
21 Oct 2010
Abstract excerpt
HIV-1 Nef has been demonstrated to be integral for viral persistence, infectivity, and the acceleration of disease pathogenesis (AIDS) in humans. Nef has also been detected in the plasma of HIV-infected individuals and is released from infected cells. The form in which Nef is released from infected cells is unknown. However, Nef is a myristoylated protein and has been shown to interact with the intracellular...
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