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Article

Proteomic profiling of SupT1 cells reveal modulation of host proteins by HIV-1 Nef variants.

PloS one - 1 Jan 2015

Saxena Reshu, Gupta Sudipti, Singh Kavita, Mitra Kalyan, Tripathi Anil Kumar, Tripathi Raj Kamal

Abstract excerpt

Nef is an accessory viral protein that promotes HIV-1 replication, facilitating alterations in cellular pathways via multiple protein-protein interactions. The advent of proteomics has expanded the focus on better identification of novel molecular pathways regulating disease progression. In this study, nef was sequenced from randomly selected patients, however, sequence variability identified did not elicited any...

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Share to Gene Expression Regulation, Viral
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Host-Parasite Interactions

Share to Jurkat Cells

Share to nef Gene Products, Human Immunodeficiency Virus

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Source

Open in PubMed Open full text

Identifiers

PMID: 25874870
DOI: 10.1371/journal.pone.0122994
PMCID: PMC4395413

Genes

ENO1
OTUB1
VDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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