Article

Exosomes from Nef expressing monocytic cells restrict HIV-1 replication in infected cells through the assembly of stress granules

2017-06-11

Abstract excerpt

Exosomes are membranous vesicles secreted from almost all types of cells, carry proteins and nucleic acids and function as vehicles for intercellular communication. Cells infected with HIV-1 or expressing the viral Nef protein secrete more exosomes than uninfected cells or those not expressing this protein. We used stably transfected, Nef-expressing U937 human monocytic cells and exosomes purified from these cells...

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Literature Corpus work: 09a64920-d62b-5db4-ae70-27bb9e812fe1
DOI: 10.1101/148791

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