Article
Rescue of developmental defects by blastocyst stem cell injection: towards elucidation of neomorphic corrective pathways.
Journal of cardiovascular translational research - 1 Feb 2010
Zhao Qingshi, Beck Amanda, Vitale Joseph M, Schneider Joel S, Terzic Andre, Fraidenraich Diego
Abstract excerpt
Stem cell-based therapy is an exciting area of high potential for regenerative medicine. To study disease prevention, we inject mouse embryonic stem cells (ESCs) into a variety of mouse blastocysts, most of which harbor mutations. Mice derived from these mutant blastocysts develop human-like dise...
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