Article
Using embryonic stem cells to introduce mutations into the mouse germ line.
Biology of reproduction - 1 Feb 1991
Robertson E J
Abstract excerpt
It is now possible, through the use of a number of experimental technologies, to transfer genetic information into mouse embryos to stably alter the genetic constitution of mice. This experimental approach, namely the generation of so-termed "transgenic" animals, is affording new insights into a...
Topics
- Animals
- Embryo, Mammalian
- Embryonic and Fetal Development
- Genetic Engineering
- Germ Cells
- Mice
- Mice, Transgenic
- Mutation
- Recombination, Genetic
- Stem Cells
- Teratoma
- Transfection