Article

Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids

2021-12-09

Abstract excerpt

<h4>ABSTRACT</h4> Directed differentiation of pluripotent stem cells (PSCs) is a powerful model system for deconstructing embryonic development. Although mice are the most advanced mammalian model system for genetic studies of embryonic development, state-of-the-art protocols for directed differentiation of mouse PSCs into defined lineages require additional steps and generate target cell types with lower purity...

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Literature Corpus work: cc4e907c-e636-5507-95f5-081a85a2f78a
DOI: 10.1101/2021.12.07.471652

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