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Article

Folate metabolism polymorphisms influence risk of colorectal adenoma recurrence.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2006

Hubner Richard A, Muir Kenneth R, Liu Jo-Fen, Sellick Gabrielle S, Logan Richard F A, Grainge Matthew, Armitage Nicholas, Chau Ian, Houlston Richard S

Abstract excerpt

Folate intake is inversely related to risk of developing colorectal neoplasia. Associations between risk of colorectal neoplasia and polymorphisms in genes coding for enzymes involved in folate metabolism have also been reported, suggesting a relationship between genotype and development of colorectal neoplasia. To further investigate the effects of folate metabolism genotypes on colorectal neoplasia, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferredoxin-NADP Reductase

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Neoplasm Recurrence, Local

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16985020
DOI: 10.1158/1055-9965.EPI-06-0274

Genes

MTHFR
MTRR
MTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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