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Article

Nonredundant roles for Runx1 alternative promoters reflect their activity at discrete stages of developmental hematopoiesis.

Blood - 15 Apr 2010

Bee Thomas, Swiers Gemma, Muroi Sawako, Pozner Amir, Nottingham Wade, Santos Ana Cristina, Li Pik-Shan, Taniuchi Ichiro, de Bruijn Marella F T R

Abstract excerpt

The transcription factor Runx1 is a pivotal regulator of definitive hematopoiesis in mouse ontogeny. Vertebrate Runx1 is transcribed from 2 promoters, the distal P1 and proximal P2, which provide a paradigm of the complex transcriptional and translational control of Runx1 function. However, very...

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Identifiers

PMID: 20139099
DOI: 10.1182/blood-2009-08-238626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20139099-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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