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Article

Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis.

BMC developmental biology - 12 Jul 2007

Pozner Amir, Lotem Joseph, Xiao Cuiying, Goldenberg Dalia, Brenner Ori, Negreanu Varda, Levanon Ditsa, Groner Yoram

Abstract excerpt

BACKGROUND: Alternative promoters usage is an important paradigm in transcriptional control of mammalian gene expression. However, despite the growing interest in alternative promoters and their role in genome diversification, very little is known about how and on what occasions those promoters are differentially regulated. Runx1 transcription factor is a key regulator of early hematopoiesis and a frequent target...

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Identifiers

PMID: 17626615
DOI: 10.1186/1471-213X-7-84
PMCID: PMC1941738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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