Article
Early ontogenic origin of the hematopoietic stem cell lineage.
Proceedings of the National Academy of Sciences of the United States of America - 20 Mar 2012
Tanaka Yosuke, Hayashi Misato, Kubota Yasushi, Nagai Hiroki, Sheng Guojun, Nishikawa Shin-Ichi, Samokhvalov Igor M
Abstract excerpt
Several lines of evidence suggest that the adult hematopoietic system has multiple developmental origins, but the ontogenic relationship between nascent hematopoietic populations under this scheme is poorly understood. In an alternative theory, the earliest definitive blood precursors arise from a single anatomical location, which constitutes the cellular source for subsequent hematopoietic populations. To...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.