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Article

Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2010

Leuenroth Stephanie J, Bencivenga Natasha, Chahboune Halima, Hyder Fahmeed, Crews Craig M

Abstract excerpt

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD), a major cause of end-stage renal failure, results from genetic mutation of either polycystin-1 (Pkd1) or polycystin-2 (Pkd2). In order to develop novel therapies to treat the advancement of disease progression, numerous rodent mode...

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Identifiers

PMID: 20139063
DOI: 10.1093/ndt/gfp777
PMCID: PMC2902895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20139063-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD.PMID 20139063Read ↗

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