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Article

Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease.

Molecules (Basel, Switzerland) - 23 Nov 2020

Millet-Boureima Cassandra, Rozencwaig Roman, Polyak Felix, Gamberi Chiara

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) causes progressive cystic degeneration of the renal tubules, the nephrons, eventually severely compromising kidney function. ADPKD is incurable, with half of the patients eventually needing renal replacement. Treatments for ADPKD patients are limited and new effective therapeutics are needed. Melatonin, a central metabolic regulator conserved across all life...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33238462
DOI: 10.3390/molecules25225477
PMCID: PMC7700119

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