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Article

Mutations in extensively drug-resistant Mycobacterium tuberculosis that do not code for known drug-resistance mechanisms.

The Journal of infectious diseases - 15 Mar 2010

Motiwala Alifiya S, Dai Yang, Jones-López Edward C, Hwang Soo-Hee, Lee Jong Seok, Cho Sang Nae, Via Laura E, Barry Clifton E, Alland David

Abstract excerpt

BACKGROUND: Highly lethal outbreaks of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are increasing. Whole-genome sequencing of KwaZulu-Natal MDR and XDR outbreak strains prevalent in human immunodeficiency virus (HIV)-infected patients by the Broad Institute identified 22 novel mutations which were unique to the XDR genome or shared only by the MDR and XDR genomes and not already...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

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Source

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Identifiers

PMID: 20136412
DOI: 10.1086/650999
PMCID: PMC2826498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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