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Article

Evolution of Mycobacterium tuberculosis drug resistance in the genomic era.

Frontiers in cellular and infection microbiology - 1 Jan 2022

Nimmo Camus, Millard James, Faulkner Valwynne, Monteserin Johana, Pugh Hannah, Johnson Eachan Oliver

Abstract excerpt

Mycobacterium tuberculosis has acquired drug resistance to all drugs that have been used against it, including those only recently introduced into clinical practice. Compared to other bacteria, it has a well conserved genome due to its role as an obligate human pathogen that has adapted to a niche over five to ten thousand years. These features facilitate reconstruction and dating of M. tuberculosis phylogenies,...

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Identifiers

PMID: 36275027
DOI: 10.3389/fcimb.2022.954074
PMCID: PMC9585206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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