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Article

Pre-detection history of extensively drug-resistant tuberculosis in KwaZulu-Natal, South Africa

28 Oct 2019

Abstract excerpt

Antimicrobial-resistant (AMR) infections pose a major threat to global public health. Similar to other AMR pathogens, both historical and ongoing drug-resistant tuberculosis (TB) epidemics are characterized by transmission of a limited number of predominant Mycobacterium tuberculosis ( Mtb ) strains. Understanding how these predominant strains achieve sustained transmission, particularly during the critical...

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PMID: 31659018
DOI: 10.1073/pnas.1906636116

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