Article
Aortic arch curvature and atherosclerosis have overlapping quantitative trait loci in a cross between 129S6/SvEvTac and C57BL/6J apolipoprotein E-null mice.
Circulation research - 2 Apr 2010
Tomita Hirofumi, Zhilicheva Svetlana, Kim Shinja, Maeda Nobuyo
Abstract excerpt
RATIONALE: Apolipoprotein E-null mice with a 129S6/SvEvTac strain background (129-apoE) develop atherosclerotic plaques faster in the aortic arch but slower in the aortic root than those with a C57BL/6J background (B6-apoE). The shape of the aortic arch also differs in the 2 strains. OBJECTIVE: B...
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