Article
Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family.
Lipids in health and disease - 1 Feb 2010
Kong Weimin, Yen Jui-Hung, Vassiliou Evros, Adhikary Sabina, Toscano Miguel G, Ganea Doina
Abstract excerpt
BACKGROUND: Acute and chronic inflammation play essential roles in inflammatory/autoimmune conditions. Protective anti-inflammatory effects of the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) were reported in animal models of colitis, sepsis, and stroke. Since dendritic cells (DC) represent the essential cellular link between innate and adaptive immunity and have a prominent role in...
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