Article
Eicosanoid-induced store-operated calcium entry in dendritic cells.
The Journal of surgical research - 1 Aug 2011
Itagaki Kiyoshi, Barton Beverly E, Murphy Thomas F, Taheri Sean, Shu Ping, Huang Hosea, Jordan Mark L
Abstract excerpt
BACKGROUND: Eicosanoids are generally recognized to exert potent immunomodulatory properties, including effects on T cell, antigen-presenting cell (APC), and dendritic cell (DC) maturation and function. Since DC maturation and function may also be regulated by store-operated calcium entry (SOCE), we hypothesized that the effects of eicosanoids on DC function may in part be regulated through changes in...
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