Article
Calpain-10 gene polymorphisms and type 2 diabetes in West Africans: the Africa America Diabetes Mellitus (AADM) Study.
Annals of epidemiology - 1 Feb 2005
Chen Yuanxiu, Kittles Rick, Zhou Jie, Chen Guanjie, Adeyemo Adebowale, Panguluri Ramesh K, Chen Weidong, Amoah Albert, Opoku Victoria, Acheampong Joseph, Agyenim-Boateng Kofi, Eghan Benjamin Ackon, Nyantaki Awuah, Oli Johnnie, Okafor Godfrey, Ofoegbu Esther, Osotimehin Babatunde, Abbiyesuku Fayeofori, Johnson Thomas, Fasanmade Olufemi, Rufus Theresa, Furbert-Harris Paulette, Daniel Harold I, Berg Kate A, Collins Francis S, Dunston Georgia M, Rotimi Charles N
Abstract excerpt
PURPOSE: To investigate whether the three single nucleotide polymorphisms (SNPs), SNP-43, -56, and -63 of CAPN10 were associated with type 2 diabetes in a West African cohort. METHODS: A total of 347 diabetic subjects and 148 unaffected controls from four ethnic groups in two West African countries were enrolled in this study. After genotyping three SNPs of CAPN10 and one SNP from CYP19, the allele, genotype, and...
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