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Article

Analysis of poly(ADP-ribose) polymerase-1 (PARP1) gene alteration in human germ cell tumor cell lines.

Cancer genetics and cytogenetics - 1 Feb 2010

Ogino Hideki, Nakayama Robert, Sakamoto Hiromi, Yoshida Teruhiko, Sugimura Takashi, Masutani Mitsuko

Abstract excerpt

The poly(ADP-ribose) polymerase-1 protein (PARP-1) functions in DNA repair, maintenance of genomic stability, induction of cell death, and transcriptional regulation. We previously analyzed alterations of the PARP1 gene in 16 specimens of human germ cell tumors, and found a heterozygous sequence...

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Source

Identifiers

PMID: 20113831
DOI: 10.1016/j.cancergencyto.2009.10.012

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20113831-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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