Article
Genetic Variation in the TP53 Gene and Patient Outcomes Following Severe Traumatic Brain Injury.
Biological research for nursing - 1 Jul 2020
Mellett Kaleigh, Ren Dianxu, Alexander Sheila, Osier Nicole, Beers Sue R, Okonkwo David O, Puccio Ava M, Conley Yvette P
Abstract excerpt
Traumatic brain injury (TBI) is a leading cause of death and disability, with more than 5 million people in the United States living with long-term complications related to TBI. This study examined the relationship between TP53, the gene that codes for the protein p53, and outcome variability following severe TBI. The p53 protein impacts neuronal apoptosis following TBI, thus investigation into TP53 genetic...
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