Article
[Clinical and prognostic significance of genetic markers of ApoE gene in traumatic brain injury].
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko - 1 Jan 2000
Potapov A A, Iusupova M M, Tendieva V D, Nikitin A G, Nosikov V V
Abstract excerpt
The review focuses on the analysis of available data about association of polymorphic genetic markers of gene encoding apolipoprotein E (APOE) with traumatic brain injury (TBI). The most investigated genetic marker of poor outcome after TBI is presence of 4 allele of APOE gene. According to most authors, carriers of this allele have worse functional outcome and lower indices of restoration of cognitive functions....
Topics
- Alleles
- Apolipoproteins E
- Brain Injuries
- Cognition
- Female
- Genetic Markers
- Humans
- Male
- Polymorphism, Genetic
- Prognosis
- Recovery of Function
