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Article

Genetic and environmental factors causing variation in drug response.

Mutation research - 1 Apr 1991

Vesell E S

Abstract excerpt

Large pharmacokinetic variations, ranging in magnitude from 4- to 40-fold, often exist among the members of a given population. These variations create differences in risk of cancer by accelerating metabolic activation of certain environmental carcinogens in some subjects, while retarding such rates in other subjects. To identify specific genetic and environmental causes of large interindividual variations in...

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Identifiers

PMID: 2011142
DOI: 10.1016/0027-5107(91)90020-o

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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