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Article

[Pharmacologic and toxicologic results in genetic polymorphisms (review)].

Ceskoslovenska fysiologie - 1 Dec 1998

Kohút A, Kalina I

Abstract excerpt

Paper provides a survey of the basic knowledge on the genetic polymorphism of enzymes involved in the metabolism of medicinal drugs and other xenobiotics. The major implications of this phenomenon have been described, namely the interindividual variability in the therapeutic effect of drugs differently metabolised by the polymorphically determined enzymes, or the interindividual variability in the susceptibility...

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PMID: 10535175

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