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Article

Novel TRIM5 isoforms expressed by Macaca nemestrina.

Journal of virology - 1 Nov 2007

Brennan Greg, Kozyrev Yury, Kodama Toshiaki, Hu Shiu-Lok

Abstract excerpt

The TRIM5 family of proteins contains a RING domain, one or two B boxes, and a coiled-coil domain. The TRIM5alpha isoform also encodes a C-terminal B30.2(SPRY) domain, differences within which define the breadth and potency of TRIM5alpha-mediated retroviral restriction. Because Macaca nemestrina animals are susceptible to some human immunodeficiency virus (HIV) isolates, we sought to determine if differences...

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Source

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Identifiers

PMID: 17804491
DOI: 10.1128/JVI.02499-06
PMCID: PMC2168977

Genes

TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Novel TRIM5 isoforms expressed by Macaca nemestrina.PMID 17804491Read ↗

The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.Semantic proximity Read ↗

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