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Article

An arginine stretch limits ADAM10 exit from the endoplasmic reticulum.

The Journal of biological chemistry - 2 Apr 2010

Marcello Elena, Gardoni Fabrizio, Di Luca Monica, Pérez-Otaño Isabel

Abstract excerpt

A disintegrin and metalloproteinase 10 (ADAM10) is a type I transmembrane glycoprotein responsible for the ectodomain shedding of a number of proteins implicated in the pathogenesis of diseases ranging from cancer to Alzheimer Disease. ADAM10 is synthesized in an inactive form, which is proteolyt...

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Identifiers

PMID: 20100836
DOI: 10.1074/jbc.M109.055947
PMCID: PMC2856244

Genes

ADAM10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20100836-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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An arginine stretch limits ADAM10 exit from the endoplasmic reticulum.PMID 20100836Read ↗

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