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Article

A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10.

Journal of neurochemistry - 1 Mar 2009

Parkin Edward, Harris Benjamin

Abstract excerpt

A disintegrin and metalloproteinase (ADAM) 10 is a type I transmembrane glycoprotein responsible for the ectodomain shedding of a range of proteins including the amyloid precursor protein implicated in Alzheimer's disease. In this study we demonstrate that ADAM10 itself is subject to shedding by...

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Identifiers

PMID: 19183255
DOI: 10.1111/j.1471-4159.2009.05907.x

Genes

ADAM10
ADAM9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19183255-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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