Article

Effects of ADAM10 gene deletion on APP shedding, neuronal synapse and cognitive function in adult mice

2024-12-20

Abstract excerpt

<title>Abstract</title> <p>A disintegrin and metalloprotease 10 (ADAM10) is a member of the large family of ADAMs (a deintegrin and metalloproteinases) which is involved in the hydrolysis of various cellular receptors and signaling molecules (such as APP etc.) for regulating the development of various organs and tissues of the body. <italic>ADAM10</italic> is an Alzheimer's disease (AD) susceptibility gene, so we...

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Literature Corpus work: bb7a3382-c4c1-55d8-975b-8b982cca16d3
DOI: 10.21203/rs.3.rs-5598577/v1

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