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Article

BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents.

NeuroImage - 15 Nov 2010

Lau Jennifer Y F, Goldman David, Buzas Beata, Hodgkinson Colin, Leibenluft Ellen, Nelson Eric, Sankin Lindsey, Pine Daniel S, Ernst Monique

Abstract excerpt

A polymorphism of the human Brain Derived Neurotrophic Factor (BDNF) gene that produces a valine-to-methionine substitution at codon 66 (Val66Met) is linked to adult anxiety and mood disorders, possibly through effects on brain circuitry function. Associations between BDNF gene variants and brain activity have not been explored in anxious and depressed adolescents. The current study investigated the association...

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Source

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Identifiers

PMID: 19931400
DOI: 10.1016/j.neuroimage.2009.11.026
PMCID: PMC2888869

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents.PMID 19931400Read ↗

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