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Article

Fine-mapping of the brain-derived neurotrophic factor (BDNF) gene supports an association of the Val66Met polymorphism with episodic memory.

The international journal of neuropsychopharmacology - 1 Sept 2010

Cathomas Flurin, Vogler Christian, Euler-Sigmund Jessica C, de Quervain Dominique J-F, Papassotiropoulos Andreas

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) plays an important role in hippocampal synaptic plasticity and long-term potentiation. A valine (Val) to methionine (Met) substitution in the BDNF gene (Val66Met) has been associated with episodic memory performance. This study aimed at fine-mapping the genomic region harbouring BDNF and the adjacent gene, BDNFOS, in order to identify other possible memory-related gene...

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Identifiers

PMID: 20482942
DOI: 10.1017/S1461145710000519

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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