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Article

Simple and accurate determination of CYP2D6 gene copy number by a loop-mediated isothermal amplification method and an electrochemical DNA chip.

Clinica chimica acta; international journal of clinical chemistry - 2 Apr 2010

Nakamura Naoko, Fukuda Tsuyoshi, Nonen Shinpei, Hashimoto Koji, Azuma Junichi, Gemma Nobuhiro

Abstract excerpt

BACKGROUND: A combination technology of a loop-mediated isothermal amplification (LAMP) method and an electrochemical DNA chip has been developed. In this study, the CYP2D6 gene copies were detected by this technology for determination of the functional CYP2D6*5 and CYP2D6*2x2 alleles. METHODS: A set of LAMP primers was designed to coamplify the CYP2D6 gene, but not the CYP2D6*36, and the CYP2D8P gene, which...

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Identifiers

PMID: 20093110
DOI: 10.1016/j.cca.2010.01.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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