Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EPHX1 polymorphisms and the risk of lung cancer: a HuGE review.

Epidemiology (Cambridge, Mass.) - 1 Jan 2006

Kiyohara Chikako, Yoshimasu Kouichi, Takayama Koichi, Nakanishi Yoichi

Abstract excerpt

BACKGROUND: Microsomal epoxide hydrolase 1 (EPHX1) plays an important role in both the activation and detoxification of tobacco-derived carcinogens. Polymorphisms at exons 3 and 4 of the EPHX1 gene have been reported to be associated with variations in EPHX1 activity. The aim of this study is to review and summarize the available molecular epidemiologic studies of lung cancer and EPHX1. METHODS: We searched...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cocarcinogenesis
Share to Epoxide Hydrolases
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Molecular Epidemiology

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 16357600
DOI: 10.1097/01.ede.0000187627.70026.23

Genes

EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EPHX1 polymorphisms and the risk of lung cancer: a HuGE review.PMID 16357600Read ↗

High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.Semantic proximity Read ↗

Association between lung cancer and microsomal epoxide hydrolase genotypes.Semantic proximity Read ↗

EPHX1 A139G polymorphism and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Functional polymorphisms of the microsomal epoxide hydrolase gene: a reappraisal on a early-onset lung cancer patients series.Semantic proximity Read ↗

Association of functionally important polymorphism of microsomal epoxide hydrolase gene (EPHX1) with lung cancer susceptibility.Semantic proximity Read ↗

The Association between EPHX1 Gene Polymorphisms and Lung Cancer among Jordanian People.Semantic proximity Read ↗

Putative EPHX1 enzyme activity is related with risk of lung and upper aerodigestive tract cancers: a comprehensive meta-analysis.Semantic proximity Read ↗

Microsomal epoxide hydrolase gene polymorphisms and susceptibility to chronic obstructive pulmonary disease in the Tunisian population.Semantic proximity Read ↗

Association between polymorphisms of microsomal epoxide hydrolase and COPD: results from meta-analyses.Semantic proximity Read ↗

Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients.Semantic proximity Read ↗

Microsomal epoxide hydrolase is not associated with COPD in a community-based sample.Semantic proximity Read ↗

Polymorphism of microsomal epoxide hydrolase is associated with chronic obstructive pulmonary disease and bronchodilator response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.