Article
Genetic association between obstructive bronchitis and enzymes of oxidative stress.
Metabolism: clinical and experimental - 1 Dec 2012
Bauer Mario, Gräbsch Carolin, Schlink Uwe, Klopp Norman, Illig Thomas, Krämer Ursula, von Berg Andrea, Schaaf Beate, Borte Michael, Heinrich Joachim, Herbarth Olf, Lehmann Irina, Röder Stefan
Abstract excerpt
OBJECTIVE: Obstructive respiratory diseases, mainly the chronic obstructive pulmonary disease (COPD) and asthma, are associated with functional polymorphisms of xenobiotic-metabolizing enzymes (XMEs). To date, association for obstructive bronchitis has not been described. MATERIAL/METHODS: In this study, we investigated the genotypes from 26 functional polymorphisms of 20 XMEs in children (n, 1028) at the age of...
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