Article
Polymorphisms in genes involved in xenobiotic metabolism and lung cancer risk under the age of 60 years. A pooled study of lung cancer patients in Denmark and Norway.
Lung cancer (Amsterdam, Netherlands) - 1 May 2005
Skuladottir Halla, Autrup Herman, Autrup Judith, Tjoenneland Anne, Overvad Kim, Ryberg David, Haugen Aage, Olsen Jørgen H
Abstract excerpt
The genetic susceptibility hypothesis has been used to explain why only a minority of smokers develop lung cancer. Only few studies have studied the role of polymorphisms in phase-I and II metabolizing genes, among young lung cancer patients. We have pooled the individual data of three studies fr...
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