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Article

Variability in drug metabolizing enzyme activity in HIV-infected patients.

European journal of clinical pharmacology - 1 May 2010

Jones Amanda E, Brown Kevin C, Werner Rebecca E, Gotzkowsky Karl, Gaedigk Andrea, Blake Mike, Hein David W, van der Horst Charles, Kashuba Angela D M

Abstract excerpt

AIMS: To evaluate variability in cytochrome P450 (CYP) 1A2, CYP2D6, CYP3A, N-acetyltransferase 2 (NAT2), and xanthine oxidase (XO) activity in HIV-infected patients and compare this with data from uninfected, healthy volunteers. METHODS: Ten HIV-infected men and seven women on medication affectin...

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Source

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Identifiers

PMID: 20084375
DOI: 10.1007/s00228-009-0777-6
PMCID: PMC2855129

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20084375-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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