Article
Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism.
British journal of clinical pharmacology - 1 Feb 2006
Burger David, van der Heiden Ilse, la Porte Charles, van der Ende Marchina, Groeneveld Paul, Richter Clemens, Koopmans Peter, Kroon Frank, Sprenger Herman, Lindemans Jan, Schenk Paul, van Schaik Ron
Abstract excerpt
AIMS: To characterize the demographic and pharmacogenetic factors that influence interpatient variability in the plasma concentrations of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz. METHODS: Data from all samples analyzed for efavirenz in our TDM service in 2002 and 2003 wer...
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