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Article

Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients.

European journal of clinical pharmacology - 1 Feb 2005

Fellay Jacques, Marzolini Catia, Decosterd Laurent, Golay Kerry Powell, Baumann Pierre, Buclin Thierry, Telenti Amalio, Eap Chin B

Abstract excerpt

OBJECTIVE: To measure the in vivo variations of CYP3A activity induced by anti-HIV drugs in human immunodeficiency virus (HIV)1-positive patients. METHODS: A low oral dose of midazolam (MID) (0.075 mg) was given to the patients and the 30-min total 1-OH midazolam (1-OHMID)/MID ratio was determined. Patients were phenotyped either before the introduction of antiretroviral treatments (control group, 90 patients) or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP3A

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Share to Oxidoreductases, N-Demethylating

Source

Identifiers

PMID: 15657782
DOI: 10.1007/s00228-004-0855-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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