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Article

COMT genotype affects prefrontal white matter pathways in children and adolescents.

NeuroImage - 15 Nov 2010

Thomason Moriah E, Dougherty Robert F, Colich Natalie L, Perry Lee M, Rykhlevskaia Elena I, Louro Hugo M, Hallmayer Joachim F, Waugh Christian E, Bammer Roland, Glover Gary H, Gotlib Ian H

Abstract excerpt

Diffusion tensor imaging is widely used to evaluate the development of white matter. Information about how alterations in major neurotransmitter systems, such as the dopamine (DA) system, influence this development in healthy children, however, is lacking. Catechol-O-metyltransferase (COMT) is th...

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Source

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Identifiers

PMID: 20083203
DOI: 10.1016/j.neuroimage.2010.01.033
PMCID: PMC2902616

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20083203-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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COMT genotype affects prefrontal white matter pathways in children and adolescents.PMID 20083203Read ↗

Met158 variant of the catechol-O-methyltransferase genotype is associated with thicker cortex in adult brain.Semantic proximity Read ↗

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COMT genotype affects brain white matter pathways in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

The COMT val158met polymorphism and brain morphometry in healthy young adults.Semantic proximity Read ↗

Variations in the catechol O-methyltransferase polymorphism and prefrontally guided behaviors in adolescents.Semantic proximity Read ↗

Effects of COMT polymorphisms on brain function and behavior in health and disease.Semantic proximity Read ↗

Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism.Semantic proximity Read ↗

Haplotypes of catechol-O-methyltransferase modulate intelligence-related brain white matter integrity.Semantic proximity Read ↗

Genetic variation in COMT and PRODH is associated with brain anatomy in patients with schizophrenia.Semantic proximity Read ↗

Magnified effects of the COMT gene on white-matter microstructure in very old age.Semantic proximity Read ↗

Effects of a functional COMT polymorphism on brain anatomy and cognitive function in adults with velo-cardio-facial syndromeSemantic proximity Read ↗

Sex-specific effects of COMT Val158Met polymorphism on corpus callosum structure: A whole-brain diffusion-weighted imaging study.Semantic proximity Read ↗

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