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Article

COMT genotype affects brain white matter pathways in attention-deficit/hyperactivity disorder.

Human brain mapping - 1 Jan 2015

Hong Soon-Beom, Zalesky Andrew, Park Subin, Yang Young-Hui, Park Min-Hyeon, Kim BoAh, Song In-Chan, Sohn Chul-Ho, Shin Min-Sup, Kim Bung-Nyun, Cho Soo-Churl, Kim Jae-Won

Abstract excerpt

Increased dopamine availability may be associated with impaired structural maturation of brain white matter connectivity. This study aimed to derive a comprehensive, whole-brain characterization of large-scale axonal connectivity differences in attention-deficit/hyperactivity disorder (ADHD) associated with catechol-O-methyltransferase gene (COMT) Val158Met polymorphism. Using diffusion tensor imaging,...

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Source

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Identifiers

PMID: 25201318
DOI: 10.1002/hbm.22634
PMCID: PMC6869623

Genes

COMT
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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