Article
The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system.
Nature - 28 Mar 1991
Hatta K, Kimmel C B, Ho R K, Walker C
Abstract excerpt
The floor plate is a set of epithelial cells present in the ventral midline of the neural tube in vertebrates that seems to have an important role in the developmental patterning of central nervous system fibre pathways, and arrangements of specific neurons. The floor plate arises from dorsal ectodermal cells closely associated with the mesoderm that forms notochord, and it may depend on interactions from the...
Topics
- Animals
- Brain
- Embryo, Nonmammalian
- Mutation
- Nerve Fibers
- Zebrafish