Article
Role of the floor plate in axonal patterning in the zebrafish CNS.
Neuron - 1 Oct 1992
Hatta K
Abstract excerpt
To determine the role of the floor plate (FP) in CNS development, I have used labeling techniques, including immunolabeling, to analyze cyclops mutant embryos, which lack the FP. Except for the anterior brain, the mutant phenotype is almost exclusively confined to the vicinity of the ventral CNS midline. In the midbrain, the number of ventral neurons is reduced and cell patterning is disturbed. In contrast, the...
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