Article
Super-sized deletions: improved transposon excision screens using a mus309 mutant background.
Fly - 1 Jan 2000
Witsell Alice, Kane Daniel P, McVey Mitch
Abstract excerpt
Over the past two decades, a large collection of transposable elements inserted at various locations in the Drosophila melanogaster genome has been assembled. These transposons are frequently utilized in imprecise excision screens to generate deletions in genes of interest. In general, these screens involve genetic manipulations to combine a non-autonomous transposon and the appropriate transposase in individual...
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