Article
A deletion-generator compound element allows deletion saturation analysis for genomewide phenotypic annotation.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 2002
Huet François, Lu Jeffrey T, Myrick Kyl V, Baugh L Ryan, Crosby Madeline A, Gelbart William M
Abstract excerpt
With the available eukaryotic genome sequences, there are predictions of thousands of previously uncharacterized genes without known function or available mutational variant. Thus, there is an urgent need for efficient genetic tools for genomewide phenotypic analysis. Here we describe such a tool: a deletion-generator technology that exploits properties of a double transposable element to produce molecularly...
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