Article
[Association between copy number variants within metabotropic glutamate receptors 7 gene and schizophrenia].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Dec 2009
Zhao Ya-li, Zhang Ke-rang, Xu Qi, Shen Yan
Abstract excerpt
OBJECTIVE: To investigate whether genomic copy number variants (CNVs), within metabotropic glutamate receptors 7 (GRM 7) gene are associated with schizophrenia. METHODS: We examined CNVs in conserved region of GRM7 using real time quantitative PCR among 180 Chinese schizophrenia cases and 33 normal controls. Products of real time quantitative PCR were sequenced bilaterally. RESULTS: Real time quantitative PCR...
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