Article
Glutamate receptor, metabotropic 7 (GRM7) gene variations and susceptibility to autism: A case-control study.
Autism research : official journal of the International Society for Autism Research - 1 Nov 2016
Noroozi Rezvan, Taheri Mohammad, Movafagh Abolfazl, Mirfakhraie Reza, Solgi Ghasem, Sayad Arezou, Mazdeh Mehrdokht, Darvish Hossein
Abstract excerpt
Autism spectrum disorder (ASD) as a synaptopathy is revealed to be pertained to aberrant glutamatergic neurotransmission. Glutamate receptor, metabotropic 7 (GRM7), a receptor coding gene of this pathway, is a new candidate gene for autism. The aim of this study was to examine if there is a relationship between genetic variants rs779867 and rs6782011 of GRM7 with ASD. The present research was designed as a...
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