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Article

Significant association of GRM7 and GRM8 genes with schizophrenia and major depressive disorder in the Han Chinese population.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jan 2016

Li Wenjin, Ju Kang, Li Zhiqiang, He Kuanjun, Chen Jianhua, Wang Qingzhong, Yang Beimeng, An Lin, Feng Guoyin, Sun Weiming, Zhou Juan, Zhang Shasha, Song Pingping, Khan Raja Amjad Waheed, Ji Weidong, Shi Yongyong

Abstract excerpt

Metabotropic glutamate receptor type 7 (GRM7) and type 8 (GRM8) are involved in the neurotransmission of glutamate which is supposed to play an important role in the development of schizophrenia (SCZ) and major depressive disorders (MDD). We designed this study to investigate whether common DNA variants or their genetic interactions within GRM7 and GMR8 genes were associated with these disorders in the Han...

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Source

Identifiers

PMID: 26655190
DOI: 10.1016/j.euroneuro.2015.05.004

Genes

GRM7
GRM8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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