Article
Peptide processing and biology in human disease.
Current opinion in endocrinology, diabetes, and obesity - 1 Feb 2009
Kovac Suzana, Shulkes Arthur, Baldwin Graham S
Abstract excerpt
PURPOSE OF REVIEW: To describe recent advances in the processing of gastrointestinal hormones, and the consequences for human disease of mutations in the enzymes involved. RECENT FINDINGS: Although gastrointestinal prohormones were long regarded as devoid of biological activity, recent data indicate that the prohormones for both gastrin and gastrin-releasing peptide are bioactive, through different receptors from...
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